Mirabegron 50 mg: Benefits, Dosage, and Side Effects

Have you ever hit that point in a diet where you’ve got no more calories to cut, you’re doing a ton of cardio every week, but that last bit of stubborn fat on your sides just won’t go away? I’ve been there too. Most people in the fitness industry would say to just keep going but you and I know that efficiency of results is what we’re all after.

Based on my experience, mirabegron is like rocket fuel for the metabolism, especially when it is in the toilet after some intense and prolonged dieting. This compound was first developed for treating overactive bladders, yet it has evolved into a performance-enhancing secret among top physique athletes.

In this article, we will discuss every essential detail about Mirabegron 50 mg from how it works to its benefits. Let’s get into it.

What is Mirabegron?

Mirabegron functions as a medication for overactive bladder treatment by relaxing the bladder so it expands during nighttime sleep. Mirabegron 50 mg plays a key role in managing an overactive bladder (OAB) and treating neurogenic detrusor overactivity (NDO), especially in adults and children over 3 years old. These conditions make it tough to control urination, leading to urgency or higher frequency. Mirabegron helps by relaxing the bladder muscle, a huge benefit if you’re over 35, and those annoying trips to the bathroom in the middle of the night are becoming more frequent.

It’s available as an extended-release tablet under brand names Myrbetriq, Betmiga and in Myrbetriq granules which are used mostly for pediatric cases. Along with reducing urinary urgency and painful urination, it’s also used to treat symptoms like urination decrease or bladder spasms linked to certain neurological conditions. 

Apart from treating overactive bladder symptoms, many recent scientific research studies have found that Mirabegron has the potential for fat loss as well. My first encounter with this compound was after researching alternative fat burners due to clenbuterol and I don’t getting along very well. What I got out of it was clen-like results without the nerve-racking palpitations and anxiety.  

How Mirabegron Works

Mirabegron works by activating beta-3 adrenergic receptors, which cause relaxation of the bladder muscle. The same receptors are found in fat tissue, especially brown adipose tissue, where they activate thermogenesis and fat oxidation.

Mirabegron works differently from Clenbuterol. Clenbuterol hits beta-1 and beta-2 receptors and can leave you jittery, anxious, or with a racing heart, while mirabegron is much more selective. It exclusively works with beta-3 receptors, giving you the fat-burning benefits without the nasty stimulant side effects. That’s what makes it an ideal option for those looking out for clean and effective fat loss, especially when paired with cold exposure or high-protein diets to supercharge brown adipose tissue (BAT) activity.

Where to Buy the Best Mirabegron 50 mg on the Market

When it comes to cutting-edge performance enhancement, Swiss Chems consistently delivers top-tier compounds backed by rigorous quality control. They test all of their products and regularly post the results on their website. 

Swiss Chems Mirabegron (50mg/capsule), 30 Capsules

Product Overview

Form: Oral capsules, 50 mg each

Dosage: 50-150 mg daily, typically split into 1-3 servings

Typical Cycle Duration: 8-12 weeks followed by 4-week break

Average Cost: $74.99

Key Benefits: Enhanced fat loss without cardiovascular stress, increased metabolic rate, improved exercise capacity, non-down regulating receptor activity, no more waking up to pee at night

Side Effects: Mild; a small increase in blood pressure, occasional headache during adaptation, mild redness of skin, stomach discomfort

Best Stack: Pairs exceptionally with GH secretagogues, L-carnitine, TRT, and SARMs for cutting phases

User Experience: Users consistently report steady fat loss without the anxiety, tremors, or sleep disruption common with other thermogenics  

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Benefits of Mirabegron

Superior Fat Loss Profile

Mirabegron can elevate your resting metabolic rate by 7–15%, meaning you’re burning more calories 24/7, even when you’re chilling. It does this without frying your nervous system or jacking up your heart rate like crazy, unlike traditional stimulants. 

Minimal Cardiovascular Impact 

While clenbuterol can spike your heart rate by 10-25 BPM, mirabegron keeps it relaxed with just a 3-5 BPM bump. You get the fat loss without feeling like your heart’s trying to escape your chest.

Activates Brown Fat

Mirabegron 50 mg mimics the effects of cold exposure by firing up your brown adipose tissue, no ice baths required. More BAT activity leads to more fat burn. Your body’s literally heating itself up by burning fat.

No Receptor Downregulation

Tolerance is one of the biggest problems with fat-burners. But mirabegron doesn’t downregulate its beta-3 receptors, making it highly effective even with extended use. No need to re-adjust the dose just to see results.

Enhanced Exercise Capacity

Mirabegron 50 mg is known to improve stamina and endurance, without negative effects like jitteriness, excessive sweating, or anxiety. Perfect for those who want to train harder without feeling like they’ve overdosed on caffeine.

Clean Drug Test Profile

And here’s the best part, Mirabegron 50 mg is not on WADA’s banned substance list (as of 2024) and is approved by the FDA. So, if you’re an athlete, you’re not risking your career to burn that little extra fat.

The thing I noticed almost immediately after using Mirabegron 50 mg was how I didn’t want to leave the gym. Also, within about two days, I noticed waking up feeling like my stomach was getting tighter and tighter.

Beginner to Advanced Dosages and Administration

• Medical Dose: 25-50 mg once daily.
• Performance Dose: 50-150 mg daily.
• Beginner Protocol: Start with 50 mg once daily to assess tolerance.
• Advanced Protocol: 50 mg morning, 50 mg pre-workout, optional 50 mg evening.
• Administration: Ideally taken with food (food reduces GI discomfort).
• Cycling: 8-12 weeks with 4-week breaks. 

If you miss a dose, use the medicine as soon as you remember, but skip the missed dose if you are more than 12 hours late. Do not use two doses at one time.

Tip: For me, I noticed the best results with taking Mirabegron 50 mg with breakfast and dinner.

Side Effects and Safety Information

• Higher doses of mirabegron, especially above the standard 50 mg, can cause slight increases in blood pressure, so it’s important to monitor if you have pre-existing hypertension.
• The primary mechanism can cause rare cases of urinary retention.
• During the adjustment phase early on, one can experience mild and short-term headaches and dizziness.
• Drug interactions involve CYP2D6 enzyme inhibition, which can modify the metabolism of other medications.
• The thermogenic effect results in a rise in body temperature between 0.1-0.3°C.
• The consumption of Mirabegron with food can help reduce gastrointestinal discomfort.
• Other rare side effects may include; serious allergic reactions, rare belching/burning feeling, bowel movement difficulty, red skin lesions on the genitals, loss of voice, muscle aches or stomach redness.

The only side effects I experienced when taking Mirabegron were slight dizziness in the first few days.

Who Should Not Use Mirabegron?

While mirabegron 50 mg is ideal for fat loss, it’s not for everyone. Here’s when you should seriously hit pause:

• Allergic Reactions: If you’re allergic to mirabegron or any of its inactive ingredients, this one’s a no-go. Allergic reactions can range from mild rashes to serious issues like breathing difficulties.
• Uncontrolled High Blood Pressure: Mirabegron can slightly raise your blood pressure, so stacking it on top of severe hypertension could put you at risk for complications like stroke or heart attack.
• Kidney or Liver Conditions: If you’re dealing with severe kidney or liver problems, your body might not process the drug properly. This could lead to a buildup of the compound and its toxicity.
• Medication Interactions: Mirabegron 50 mg can interact with certain drugs, especially those metabolized through the CYP3A4 pathway, leading to dangerous side effects or reduced effectiveness. Always check with your healthcare provider before adding it to your stack.
• History of Severe Angioedema: If you’ve ever had a serious episode of angioedema (swelling under the skin that can block airways), mirabegron might not be worth the risk.
• Under 18 Years Old: This compound is recommended for adults only. If you’re under 18, it’s only recommended to be used under strict medical supervision.

Always consult a healthcare professional before incorporating Mirabegron in your routine especially if you have pre-existing medical conditions, like kidney disease, to avoid any unwanted side effects. 

Interactions with Other Medicines

Mirabegron inhibits CYP2D6 enzymes, creating potential interactions with the following drugs:

• Digoxin (increased levels)
• Beta-blockers (enhanced effects)
• Antiarrhythmics (flecainide, propafenone)
• Antipsychotics (especially thioridazine)
• SSRIs (fluoxetine, paroxetine)
• ADHD medications (amphetamine-based)
• Opioids (altered metabolism)

Higher doses of Mirabegron (100-150 mg) intensify these interactions. If you accidentally overdose on Mirabegron, seek medical help right away or contact your nearest poison control center.

Additional Information About Mirabegron 50 mg

• A 200 mg dose of Mirabegron enlarges the gallbladder by 35%, which could enhance metabolic performance.
• The combination of Mirabegron with cold exposure therapy leads to greater brown fat activation, which pushes your body into an intense fat-burning mode.
• May have prostate benefits in addition to its fat loss properties, as it reduces the symptoms of benign prostatic hyperplasia (BPH).
• Preserves muscle tissue during cutting phases which sets it apart from other thermogenic agents. For athletes and bodybuilders, that means shredding fat while holding onto muscle, which is the ultimate win during cutting phases.

Disclaimer: None of the information in this article is medical advice. Always consult your healthcare provider before considering taking any new medications or supplements. If you have any questions or concerns, talk to your healthcare provider.

Conclusion

Mirabegron may have started as a solution for overactive bladders, but science and biohackers are now uncovering its potential in the world of fat loss and metabolism. Medical professionals who serve as gatekeepers are either uneducated or fail to disclose Mirabegron’s performance-enhancing uses that extend beyond bladder management. But if you’re like me, always questioning the narrative in pursuit of results, you’ll recognize the value of this drug while in a fat loss phase.

When used responsibly, Mirabegron 50 mg stands as a revolutionary medication because it delivers results without having to accept the traditional side effects that come with old-school methods like clenbuterol and thyroid drugs. No more choosing between results and performance.

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