The Morning Dose #31: Peptide Stacking, Infertility, and the Fountain of Youth

In this week’s edition of The Morning Dose:

What is Peptide Stacking?

Infertility and the Reproductive Microbiome

 Is Your Insulated Cup a Health Risk?

Research Corner: T-Cells Are The Fountain of Youth

Let’s inject this.

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 What is Peptide Stacking?

In the world of peptides, one common topic you’ll see is the idea of peptide stacking, which involves using multiple peptides that work together to create a stronger effect.

Rather than simply increasing your dose of a single peptide, you can mix and match peptides to create a protocol that’s custom-tailored to your individual goals.

Whether your goal is fat loss, muscle growth, or anti-aging, stacking peptides can help you get there faster.

So how does it work?

For example, let’s think about the goal of fat loss. One common protocol is the semaglutide and AOD 9604 stack.

Semaglutide primarily helps control the appetite and drive to eat, while AOD 9604 increases fat burning and blunts fat storage.

Sure, people using semaglutide may increase their dose to break plateaus, but there are better ways.

Rather than one or the other, the combined effect of neutralizing your appetite AND increasing fat burning delivers even better results.

For building muscle, you stack Ipamorelin and CJC 1295, both of which increase growth hormone production, making fat loss and muscle building even easier.

While increasing your dose of a single peptide can work, sometimes the best results come from combining multiple peptides.

We also recommend using individual peptides so that you can control the dosing of each.

Many peptide companies sell pre-made blends, which can work well, but you can’t adjust the ratio of each peptide to fit your needs.

Peptide stacking is a fantastic way to get better results by combining synergistic peptides, and a great way for intermediate peptide users to take their health optimization to the next level.

To learn more about peptide stacking, and learn what we consider to be the best peptide combinations, check out our guide to the best peptide stacks right here.

  Infertility and the Reproductive Microbiome

Here’s an interesting one that came across our desk recently…

A new study showed that the microbiome of your semen is directly linked to male infertility.

Over the years, we’ve long known that the reproductive health of both men and women has been in decline. Guys in their 20s and 30s legitimately need TRT, and infertility rates are soaring.

Researchers have primarily looked at lifestyle factors like exercise, smoking, and alcohol intake, or environmental pollution and toxins that disrupt our hormones.

But now, researchers are looking at the living bacteria in your semen. Yes, it contains living bacteria, just like your gut microbiome.

Anyway, the study found that the men in their study who had reproductive issues and were seeking fertility treatment all had higher than normal levels of a bacteria called L. iners.

Now, the study authors made it clear that more research is needed, and this is really the first time people have started to test the relationship between the microbiome and fertility.

In other words, if you’re struggling with fertility, rushing out to buy probiotics may not be the solution. We simply don’t know yet.

However, given that many of our readers are already using things like TRT and peptides, which can also impact fertility, this is yet another fascinating area of research that we’ll be keeping a very close eye on!

Is Your Insulated Cup a Health Risk?

If you’ve checked social media at all in the past couple of months, you’ve no doubt seen those gigantic insulated Stanley Cups that are so in demand they’re causing legitimate safety issues at retail stores.

Everywhere you look, you’ll see someone with a huge insulated cup. And hey, we’re not knocking the trend at all–hydration is important, and this trend seems to be helping people drink more water.

However, there’s one concern…

TikTok has become flooded with videos of users doing lead tests in Stanley Cups, and nearly all of them are testing positive.

Lead toxicity in humans is quite serious, and not something you want to mess with.

Now, Stanley has addressed this by claiming that the lead is used as insulation, and is sealed behind a layer of stainless steel. They claim the lead is inaccessible.

Experts say that the cups should be safe as long as the stainless steel interior remains intact, and it seems like that would be pretty hard to break accidentally.

Still, knowing there’s only a thin layer of stainless steel between your water and lead is a bit discomforting.

Our advice?

If you already have one (or more!) Stanley Cups, don’t throw them away! Check your cup periodically, and if you don’t see any internal damage, you should be just fine.

But, it is worth keeping an eye on, and if you drop or damage your Stanley cup and notice any visible damage to the inside, you probably want to replace it.

Here’s a link to a longer version of the story on CNN, though just about every news outlet has covered this by now.

Research Corner: T-Cells Are The Fountain of Youth

Let’s dive into another fascinating study, one that has nothing to do with the reproductive system this time.

This time, we’re talking about T cells, which are cells in the body that support a healthy immune system.

In a new study, researchers found that genetically reprogramming these T cells caused them to eliminate senescent cells in the body, which are aging, dying cells.

This was a rodent study, so we’re not really close to human trials yet, but the early results were a bit shocking.

When mice were treated with modified T cells, called CAR T cells, they experienced clinically significant health improvements, including reduced body weight, a faster metabolism, and a higher level of daily activity.

These are the most important changes, but those senescent cells that are eliminated by treated T cells have also been associated with things like cognitive decline and aging skin, so using these modified T cells may truly slow and reverse all kinds of aging.

The best part?

These trials were performed on mice… but the exact same kind of CAR T cells are currently being used to help fight certain types of blood cancers.

So we know that humans can use CAR T cells, and we know they’re extremely potent at slowing aging and improving health in mice… it seems like human trials may not be all that far away.

We’ll keep you updated on future research, as always, but this one is really exciting.

If we can use natural cells to slow and reverse aging, we’re one step closer to truly unlocking the fountain of youth.

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