The Benefits of Nitric Oxide

[NGear]

What comes to mind when you hear the word nitric oxide (NO)? Isn't it likely that you're thinking of a dentist's office? The trouble is, instead of nitric oxide, they employ nitrous oxide. Nitric oxide is a whole distinct substance, and while you may be familiar with "laughing gas" at the dentist...

[drtbear1967]

One of the newest nootropic supplements on the market is methylliberine, most commonly seen as the branded Dynamine. Methylliberine is known as a methylurate, which differs structurally from methylxanthines(caffeine, theobromine) by having an oxo group on the 5 membered ring, and is more similar to...

[drtbear1967]

Huperzine A is an all natural nootropic molecule that is commonly found in many top selling cognitive enhancement products. It works by inhibiting the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine. Acetylcholine is responsible for not only cognitive function and learning,...

[drtbear1967]

There is a trend now with preworkout/energy supplements incorporating nootropics in the formula, along with your normal stimulants. I really like this direction and the combination of nootropics and stimulants works very well, IMO. Noopept is a unique molecule that is usually classified as a racetam...

[drtbear1967]

theguerillachemist

I get a lot of questions about nootropics and since they all increase choline/acetylcholine levels why can't you just take choline(bitartrate)? The answer lies in the image here: A is Dimethylaminoethanol and B is Choline. Choline is a positively charged molecule(4 bonds...

[drtbear1967]

theguerillachemist

Palmitoylethanolamide (PEA) is your body's natural anti-inflammatory molecule that is endogenously produced during periods of inflammation. It was first discovered in the 1930s and was isolated from egg yolk, and since then has had over 500 published studies on it. PEA...

[drtbear1967]

In 2013, a stimulant drink called Clearshot by E-Pharm was released and it was formulated by none other than infamous chemist Patrick Arnold. It contained an ambiguously named stimulant “2-aminoisoheptane” that no one had really heard of at this point. Reviews for this product were very

...

[drtbear1967]

theguerillachemist AICAR(Acadesine monophosphate aka ZMP) is a very cool molecule that has been making its way into the performance enhancing circles, and even more recently being sold as a supplement. AICAR is an analog of adenosine(AMP/ATP) that acts as an AMPK agonist. AMPK is an enzyme that regula...

[drtbear1967]

Palmitoylethanolamide(PEA) is your body's natural anti-inflammatory molecule that is endogenously produced during periods of inflammation. It was first discovered in the 1930s and was isolated from egg yolk, and since then has had over 500 published studies on it. PEA works by reducing the activati...

[drtbear1967]

There is a trend now with preworkout supplements incorporating nootropics in the formula, along with your normal stimulants. I really like this direction and the combination of nootropics and stimulants works very well, IMO. Noopept is a synthetic molecule very usually classified as a racetam derivative....

[drtbear1967]

theguerillachemist As you may know, testosterone and many other androgens can be converted in the body to DHT via the enzyme 5alpha reductase(5aR). This enzyme adds 2 hydrogen atoms across the double bond between carbons 4 and 5. However, trenbolone cannot be reduced by 5aR. Why not? It has a 4-5 doub...

[teeg]

2. The Shape of Simple Carbon Compounds

Aede de Groot, Willem Koert In the previous chapter we have described that organic chemists, biochemists and pharmacists together try to develop optimal compounds for the biological process that has to be stimulated. For this purpose first of al...